Gene-expression based disease class classification using probit model

نویسندگان

  • Hideyuki Takahashi
  • Toshimasa Yamazaki
  • Hiroki Sasaki
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Feature Selection and Classification of Microarray Gene Expression Data of Ovarian Carcinoma Patients using Weighted Voting Support Vector Machine

We can reach by DNA microarray gene expression to such wealth of information with thousands of variables (genes). Analysis of this information can show genetic reasons of disease and tumor differences. In this study we try to reduce high-dimensional data by statistical method to select valuable genes with high impact as biomarkers and then classify ovarian tumor based on gene expression data of...

متن کامل

Multi-class cancer classification using multinomial probit regression with Bayesian gene selection.

We consider the problems of multi-class cancer classification from gene expression data. After discussing the multinomial probit regression model with Bayesian gene selection, we propose two Bayesian gene selection schemes: one employs different strongest genes for different probit regressions; the other employs the same strongest genes for all regressions. Some fast implementation issues for B...

متن کامل

پیش بینی ژن‏ های بیماری با استفاده از دسته‏ بند تک‌کلاسی ماشین بردار پشتیبان

Abstract: In disease gene identification and classification, users are only interested in classifying one specific class, disease genes, without considering other classes (non-disease genes). This situation is referred to as one-class classification. Existing machine learning-based methods typically use known disease gene as positive training set and unknown genes as negative training set to bu...

متن کامل

Mammalian Eye Gene Expression Using Support Vector Regression to Evaluate a Strategy for Detecting Human Eye Disease

Background and purpose: Machine learning is a class of modern and strong tools that can solve many important problems that nowadays humans may be faced with. Support vector regression (SVR) is a way to build a regression model which is an incredible member of the machine learning family. SVR has been proven to be an effective tool in real-value function estimation. As a supervised-learning appr...

متن کامل

Modification of the Fast Global K-means Using a Fuzzy Relation with Application in Microarray Data Analysis

Recognizing genes with distinctive expression levels can help in prevention, diagnosis and treatment of the diseases at the genomic level. In this paper, fast Global k-means (fast GKM) is developed for clustering the gene expression datasets. Fast GKM is a significant improvement of the k-means clustering method. It is an incremental clustering method which starts with one cluster. Iteratively ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2009